Disclaimer: I am not a biologist. I am a curious individual who has sought to formalize the ideas presented in a nonfiction best seller. My goal is to inspire a mental model that makes it easier to study the field of aging, not to provide educational resources for the field of biology. In Lifespan: Why We Age and Why We Don’t Have To , Dr. Sinclair presents to us his Information Theory of Aging. The Information Theory of Aging states that the aging process is driven by the progressive loss of epigenetic information. In order to explore his arguments, we first have to define ‘aging process’ and ‘epigenetic information’. Aging Process We shall define the aging process 𝛂 as a sequence e[0] e[1] … e[N]. Each element e[i] of this sequence is a tuple of 5 sets, one for each phase of the cell (G0, G1, S, G2, M). Each set includes three members: (1) a set of proteins and the quantity of such proteins produced by the ith division of the cell. (2) Epigenetic information (which genes ...